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Peripheral membrane proteins: FYVE sticky fingers

1999; Elsevier BV; Volume: 9; Issue: 22 Linguagem: Inglês

10.1016/s0960-9822(00)80046-9

1879-0445

Paul C. Driscoll, Annelise Vuidepot,

RNA and protein synthesis mechanisms

The recently determined structure of the lipid-binding ‘FYVE’ domain provides several clues to the mode of interaction for this class of peripheral membrane proteins. However, the application of traditional modes of structural analysis to diffusible membrane-binding proteins exposes some limitations of these techniques.