Vaginal Cancer after Maternal Treatment with Synthetic Estrogens
1971; Massachusetts Medical Society; Volume: 285; Issue: 7 Linguagem: Inglês
10.1056/nejm197108122850707
ISSN1533-4406
AutoresPeter Greenwald, Joseph J. Barlow, Philip C. Nasca, William S. Burnett,
Tópico(s)Cancer Risks and Factors
ResumoVAGINAL adenocarcinoma in young women was recently reported by Herbst, Ulfelder and Poskanzer1 as being associated with stilbestrol therapy of the mother during pregnancy. In an accompanying editorial, Dr. Alexander D. Langmuir2 emphasized the scientific and social implications of this observation, and stated the need for confirmatory data. Our findings confirm the association and provide additional information on dose and time relations.The New York State Cancer Registry receives reports of all cancer diagnosed in New York State, exclusive of New York City. During the period 1950 through 1970, five adenocarcinomas of the vagina were reported in women under age . . .
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