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Solvolytic desulfation of 2-deoxy-2-sulfoamino-D-glucose and D-glucose 6-sulfate

1974; Elsevier BV; Volume: 36; Issue: 2 Linguagem: Inglês

10.1016/s0008-6215(00)83047-5

1873-426X

Kinzo Nagasawa, Yuko Inoue,

Aldose Reductase and Taurine

Solvolytic desulfation of the pyridinium salts of 2-deoxy-2-sulfoamino-D-glucose and D-glucose 6-sulfate in dimethyl sulfoxide containing 5% of water or methanol was studied to develop a method for selective N-desulfation of heparin. The first-named salt was the most susceptible to N-desulfation.