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The utilization of the α-glycerophosphate and monoglyc- eride pathways for phosphatidyl choline biosynthesis in the intestine

1970; Elsevier BV; Volume: 218; Issue: 1 Linguagem: Inglês

10.1016/0005-2760(70)90099-8

1879-145X

John M. Johnston, Fritz Paultauf, Carol M. Schiller, Linda D. Schultz,

Metabolism and Genetic Disorders

1. It has been shown that the diglycerides synthesized via the monoglyceride pathway are not incorporated into phosphatidyl choline while the diglycerides synthesized via the α-glycerophosphate pathway are a precursor of phosphatidyl choline. 2. The stereochemical configuration of the diglyceride synthesized by both pathways is the sn-1,2-configuration. 3. The relationship of the two microsomal diglyceride pools to triglyceride and phosphatidyl choline by synthesis in the intestine is discussed.