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Cover Picture: Quantification of Photosensitized Singlet Oxygen Production by a Fluorescent Protein (ChemPhysChem 1/2011)

2011; Wiley; Volume: 12; Issue: 1 Linguagem: Inglês

10.1002/cphc.201190000

1439-7641

Xavier Ragàs, Laurie P. Cooper, John H. White, Santi Nonell, Cristina Flors,

Photodynamic Therapy Research Studies

ChemPhysChemVolume 12, Issue 1 p. 1-1 Cover PictureFree Access Cover Picture: Quantification of Photosensitized Singlet Oxygen Production by a Fluorescent Protein (ChemPhysChem 1/2011) Dr. Xavier Ragàs, Dr. Xavier Ragàs Grup d′Enginyeria Molecular, Institut Químic de Sarrià, Via Augusta 390, 08017 Barcelona (Spain), Fax: (+34) 93-205-6266Search for more papers by this authorLaurie P. Cooper, Laurie P. Cooper EastChem School of Chemistry, University of Edinburgh, Joseph Black Building, The King′s Buildings, West Mains Rd, EH9 3JJ Edinburgh (UK), Fax: (+44) 131 650 6453Search for more papers by this authorDr. John H. White, Dr. John H. White EastChem School of Chemistry, University of Edinburgh, Joseph Black Building, The King′s Buildings, West Mains Rd, EH9 3JJ Edinburgh (UK), Fax: (+44) 131 650 6453Search for more papers by this authorProf. Santi Nonell, Corresponding Author Prof. Santi Nonell [email protected] Grup d′Enginyeria Molecular, Institut Químic de Sarrià, Via Augusta 390, 08017 Barcelona (Spain), Fax: (+34) 93-205-6266 Santi Nonell, Grup d′Enginyeria Molecular, Institut Químic de Sarrià, Via Augusta 390, 08017 Barcelona (Spain), Fax: (+34) 93-205-6266 Cristina Flors, EastChem School of Chemistry, University of Edinburgh, Joseph Black Building, The King′s Buildings, West Mains Rd, EH9 3JJ Edinburgh (UK), Fax: (+44) 131 650 6453Search for more papers by this authorDr. Cristina Flors, Corresponding Author Dr. Cristina Flors [email protected] EastChem School of Chemistry, University of Edinburgh, Joseph Black Building, The King′s Buildings, West Mains Rd, EH9 3JJ Edinburgh (UK), Fax: (+44) 131 650 6453 Santi Nonell, Grup d′Enginyeria Molecular, Institut Químic de Sarrià, Via Augusta 390, 08017 Barcelona (Spain), Fax: (+34) 93-205-6266 Cristina Flors, EastChem School of Chemistry, University of Edinburgh, Joseph Black Building, The King′s Buildings, West Mains Rd, EH9 3JJ Edinburgh (UK), Fax: (+44) 131 650 6453Search for more papers by this author Dr. Xavier Ragàs, Dr. Xavier Ragàs Grup d′Enginyeria Molecular, Institut Químic de Sarrià, Via Augusta 390, 08017 Barcelona (Spain), Fax: (+34) 93-205-6266Search for more papers by this authorLaurie P. Cooper, Laurie P. Cooper EastChem School of Chemistry, University of Edinburgh, Joseph Black Building, The King′s Buildings, West Mains Rd, EH9 3JJ Edinburgh (UK), Fax: (+44) 131 650 6453Search for more papers by this authorDr. John H. White, Dr. John H. White EastChem School of Chemistry, University of Edinburgh, Joseph Black Building, The King′s Buildings, West Mains Rd, EH9 3JJ Edinburgh (UK), Fax: (+44) 131 650 6453Search for more papers by this authorProf. Santi Nonell, Corresponding Author Prof. Santi Nonell [email protected] Grup d′Enginyeria Molecular, Institut Químic de Sarrià, Via Augusta 390, 08017 Barcelona (Spain), Fax: (+34) 93-205-6266 Santi Nonell, Grup d′Enginyeria Molecular, Institut Químic de Sarrià, Via Augusta 390, 08017 Barcelona (Spain), Fax: (+34) 93-205-6266 Cristina Flors, EastChem School of Chemistry, University of Edinburgh, Joseph Black Building, The King′s Buildings, West Mains Rd, EH9 3JJ Edinburgh (UK), Fax: (+44) 131 650 6453Search for more papers by this authorDr. Cristina Flors, Corresponding Author Dr. Cristina Flors [email protected] EastChem School of Chemistry, University of Edinburgh, Joseph Black Building, The King′s Buildings, West Mains Rd, EH9 3JJ Edinburgh (UK), Fax: (+44) 131 650 6453 Santi Nonell, Grup d′Enginyeria Molecular, Institut Químic de Sarrià, Via Augusta 390, 08017 Barcelona (Spain), Fax: (+34) 93-205-6266 Cristina Flors, EastChem School of Chemistry, University of Edinburgh, Joseph Black Building, The King′s Buildings, West Mains Rd, EH9 3JJ Edinburgh (UK), Fax: (+44) 131 650 6453Search for more papers by this author First published: 12 January 2011 https://doi.org/10.1002/cphc.201190000Citations: 8AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat Graphical Abstract The picture shows the red fluorescent protein TagRFP, which is able to photosensitize singlet oxygen, with an estimated quantum yield of ΦΔ≈0.004, as described by S. Nonell, C. Flors et al. on p. 161. This is the first estimation of a ΦΔ value for a GFP-like protein. Moreover, the short triplet lifetime of TagRFP suggests relatively high oxygen accessibility to the chromophore compared to other fluorescent proteins. These results have implications in improving fluorescent proteins for fluorescence microscopy and chromophore-assisted laser inactivation. Citing Literature Volume12, Issue1January 17, 2011Pages 1-1 RelatedInformation