Portal de Periódicos da CAPES

Significance of Mitochondria for Porphyrin and Heme Biosynthesis

1959; American Association for the Advancement of Science; Volume: 129; Issue: 3344 Linguagem: Inglês

10.1126/science.129.3344.275

1095-9203

Seiyo Sano, Susumu Inoue, Yoichi Tanabe, C Sumiya, Shiro Koike,

Photosynthetic Processes and Mechanisms

It is concluded that mitochondria are involved in three steps of porphyrin and heme biosynthesis-first, in the formation of delta-aminolevulinic acid from glycine and active succinate; second, in the synthesis of protoporphyrin; third, in the incorporation of iron into the porphyrin ring-that is, in heme formation.