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Bromopyrrole Alkaloids from Marine Sponges of the Genus Agelas

2009; American Chemical Society; Volume: 72; Issue: 3 Linguagem: Inglês

10.1021/np800645q

1520-6025

Tetsuro Yasuda, Atsushi Araki, Takaaki Kubota, Junji Ito, Yuzuru Mikami, Jane Fromont, Jun’ichi Kobayashi,

Microbial Natural Products and Biosynthesis

Four new bromopyrrole alkaloids, nagelamides O (1) and P (2) and mukanadins E (3) and F (4), were isolated from three collections of Okinawan marine sponges of the genus Agelas. The structures and stereochemistry of 1−4 were elucidated on the basis of their spectroscopic data.