Cytomegalovirus Infection in Normal and Immunocompromised Humans
2000; Karger Publishers; Volume: 200; Issue: 3 Linguagem: Inglês
10.1159/000018381
ISSN1421-9832
AutoresFilippo Drago, Maria Grazia Aragone, Cesare Lugani, Alfredo Rebora,
Tópico(s)Herpesvirus Infections and Treatments
ResumoAlthough cytomegalovirus (CMV) disease is a severe complication among immunocompromised patients, its cutaneous features have not been reported frequently. CMV belongs to the Herpesviridae family sharing with the other members the ability to remain latent in their natural hosts after an initial infection and to produce overt disease in several settings. The natural history of human CMV infection is characterized by primary infection, latent infection and reinfection. This article reviews the extremely variable aspects of the clinical presentation of CMV infection in normal and immunocompromised humans, focusing on the dermatological manifestations, and indicates the laboratory tests for detecting CMV responsibility in skin disorders.
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