Artigo Revisado por pares

An immunologically active arabinogalactan from Viscum album ‘berries’

1988; Elsevier BV; Volume: 27; Issue: 8 Linguagem: Inglês

10.1016/0031-9422(88)87019-5

ISSN

1873-3700

Autores

Hildebert Wagner, E. Jordan,

Tópico(s)

Galectins and Cancer Biology

Resumo

From Viscum album 'berries', a complex acidic arabinogalactan (Fb) with mean Mr of 700 000 has been isolated by DEAE-Trisacryl M column chromatography and by affinity chromatography on Sephacryl S 1000 bound Ricinus communis lectin and separated into two arabinogalactan-fractions (RCA-N and RCA-G). Their structures were elucidated mainly by methylation analysis, partial acidic hydrolysis and 15C-NMR spectroscopy. The acidic arabinogalactan Fb stimulates in vitro the alternative pathway of the human complement system.

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