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Production of Lactate and Tissue Plasminogen Activator in Vitro by Seminiferous Tubules Obtained From Adult Unilaterally Cryptorchid Rats

1987; Taylor & Francis; Volume: 19; Issue: 2 Linguagem: Inglês

10.3109/01485018708986813

1521-0375

Anders Bergh, J‐E. Damber, Hans Jacobsson, Tobias Nilsson,

Reproductive Biology and Fertility

Pieces of seminiferous tubules obtained from adult unilaterally cryptorchid rats were incubated in vitro and the effect of FSH on the secretion of lactate and tissue-plasminogen activator (t-PA) was studied. Tubules from abdominal testes secreted less lactate than scrotal tubules. On the other hand, the basal secretion of t-PA was similar but the FHS-stimulated t-PA secretion was larger from abdominal than from scrotal tubules. These results indicate a more specific dysfunction of the Sertoli cells in crypt-orchidism than earlier recognized.