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Linac-based or robotic image-guided stereotactic radiotherapy for isolated lymph node recurrent prostate cancer

2009; Elsevier BV; Volume: 93; Issue: 1 Linguagem: Inglês

10.1016/j.radonc.2009.04.001

1879-0887

Barbara Alicja Jereczek‐Fossa, Laura Fariselli, G. Beltramo, Gianpiero Catalano, Flavia Serafini, Cristina Garibaldi, Raffaella Cambria, Lorenzo Brait, M. Possanzini, Livia Bianchi, Andrea Vavassori, Dario Zerini, Franco Orsi, Ottavio De Cobelli, Roberto Orecchia,

Prostate Cancer Treatment and Research

We report on 14 patients treated with linac- or robotic image-guided stereotactic radiotherapy for isolated lymph node recurrence from prostate cancer, up to the mean dose of 30Gy/3 fractions. At the mean follow-up of 18.6months, five patients experienced clinical out-field progression. Toxicity was minimal. Further investigation is warranted in order to identify the patients that benefit most from this treatment modality and to define the optimal association of such local approach with androgen deprivation. Hopefully, effective local therapy might reduce the burden of systemic therapies given to the recurrent/metastatic prostate cancer patients.