Chromatid-type aberrations following irradiation in G0 lymphocytes with heavy ions

2007; Elsevier BV; Volume: 617; Issue: 1-2 Linguagem: Inglês

10.1016/j.mrfmmm.2007.01.003

ISSN

1873-135X

Autores

Zhuanzi Wang, Wenjian Li, Zhi Dejuan, Wei Wei, Jing Xigang, Qingxiang Gao,

Tópico(s)

Carcinogens and Genotoxicity Assessment

Resumo

We describe a low level of chromatid-type aberrations which included the relatively rare isochromatid/chromatid triradial in peripheral blood lymphocytes that were irradiated, ostensibly in G0, with accelerated heavy (12)C ions. These were produced only at the energies of 69 MeV/n (34.6 keV/microm), almost absent at the energy of either 58.6 MeV/n (46.07 keV/ microm) or 19.3 MeV/n (97 keV/microm), nor were they found after low-LET X-rays. Mechanisms potentially responsible for their formation are discussed.

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