Antenatal Diagnostic Aspects of Unilateral Multicystic Kidney Dysplasia – Sensitivity, Specificity, Predictive Values, Differential Diagnoses, Associated Malformations and Consequences
2004; Karger Publishers; Volume: 19; Issue: 2 Linguagem: Inglês
10.1159/000075143
ISSN1421-9964
AutoresF. Eckoldt, R. Woderich, Daron Smith, K. S. Heling,
Tópico(s)Urological Disorders and Treatments
Resumo<i>Objectives:</i> Unilateral multicystic kidney dysplasia (MCKD) is the second most common urinary tract abnormality diagnosed antenatally. Whilst an isolated unilateral MCKD has a good prognosis, a poor outcome must be expected when MCKD is associated with other complex abnormalities. <i>Material:</i> Out of 11,176 cases, 693 fetuses were suspected of having urinary tract abnormalities. Urological findings were confirmed in 548 of them. Unilateral cystic kidney was diagnosed prenatally in 85 cases. <i>Results:</i> The study results in a total of 107 cases with proven MCKD. Eighty-five pregnancies with a prenatal diagnosis of MCKD were analysed. The antenatal diagnosis of MCKD was confirmed in 56 cases. Fifty-one children were found to have unilateral MCKD where this had not been explicitly suspected from antenatal scanning. <i>Conclusion:</i> Unilateral MCKD is a malformation with an excellent prognosis for child survival and global renal function if encountered in isolation. However, our analysis of live infants and autopsy cases demonstrates a high proportion of severe associated malformations of the urinary tract and other organ systems.
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