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Efficacy of Monascus purpureus Went rice on lowering lipid ratios in hypercholesterolemic patients

2007; SAGE Publishing; Volume: 14; Issue: 3 Linguagem: Inglês

10.1097/hjr.0b013e32801da137

1741-8275

Chien-Fang Huang, Tsai-Chung Li, Cheng‐Chieh Lin, Chiu-Shong Liu, Hung-Chang Shih, Ming-May Lai,

Pharmacological Effects of Natural Compounds

Several lipid ratios may be predictors of coronary artery disease risk. We assessed the efficacy of Monascus purpureus Went rice (red yeast rice) on lowering lipid ratios. We evaluated 79 hypercholesterolemic patients (aged 23-65 years) who received a twice-daily dose of either red yeast rice or a placebo at 600 mg for 8 weeks. The 8-week treatment with red yeast rice showed significantly greater reduction than the placebo treatment in low-density lipoprotein cholesterol levels, total cholesterol/high-density lipoprotein cholesterol, low-density lipoprotein cholesterol/high-density lipoprotein cholesterol and apolipoprotein B/apolipoprotein A-I ratios. Red yeast rice can reduce lipid ratios in hypercholesterolemic patients.