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Structural Basis for Activation and Inhibition of Class I Phosphoinositide 3-Kinases

2011; American Association for the Advancement of Science; Volume: 4; Issue: 195 Linguagem: Inglês

10.1126/scisignal.2002165

1937-9145

Oscar Vadas, John E. Burke, Xuxiao Zhang, Alex Berndt, Roger Williams,

Protein Kinase Regulation and GTPase Signaling

The regulatory interactions between PI3Ks and their binding partners could be exploited for therapies.