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Pharmacokinetics of [ 3 H]‐ivermectin in the dog following oral administration of a beef‐based chewable formulation containing ivermectin alone or in combination with pyrantel pamoate

1992; Wiley; Volume: 15; Issue: 2 Linguagem: Inglês

10.1111/j.1365-2885.1992.tb01009.x

1365-2885

Jason Clark, Carolyn P. Daurio, B.J. Skelly, Ellen Cheung, A. Robert Jeffcoat,

Veterinary Pharmacology and Anesthesia

Journal of Veterinary Pharmacology and TherapeuticsVolume 15, Issue 2 p. 217-220 Pharmacokinetics of [3H]-ivermectin in the dog following oral administration of a beef-based chewable formulation containing ivermectin alone or in combination with pyrantel pamoate J. N. CLARK, J. N. CLARK Merck, Sharp and Dohme Research Laboratories, Rahway, New Jersey, 07065–9014Search for more papers by this authorC. P. DAURIO, C. P. DAURIO Merck, Sharp and Dohme Research Laboratories, Rahway, New Jersey, 07065–9014Search for more papers by this authorB. J. SKELLY, B. J. SKELLY Merck, Sharp and Dohme Research Laboratories, Rahway, New Jersey, 07065–9014Search for more papers by this authorE. N. CHEUNG, E. N. CHEUNG *Research Triangle Institute, Research Triangle Park, North Carolina, USASearch for more papers by this authorA. R. JEFFCOAT, A. R. JEFFCOAT *Research Triangle Institute, Research Triangle Park, North Carolina, USASearch for more papers by this author J. N. CLARK, J. N. CLARK Merck, Sharp and Dohme Research Laboratories, Rahway, New Jersey, 07065–9014Search for more papers by this authorC. P. DAURIO, C. P. DAURIO Merck, Sharp and Dohme Research Laboratories, Rahway, New Jersey, 07065–9014Search for more papers by this authorB. J. SKELLY, B. J. SKELLY Merck, Sharp and Dohme Research Laboratories, Rahway, New Jersey, 07065–9014Search for more papers by this authorE. N. CHEUNG, E. N. CHEUNG *Research Triangle Institute, Research Triangle Park, North Carolina, USASearch for more papers by this authorA. R. JEFFCOAT, A. R. JEFFCOAT *Research Triangle Institute, Research Triangle Park, North Carolina, USASearch for more papers by this author First published: June 1992 https://doi.org/10.1111/j.1365-2885.1992.tb01009.xCitations: 4AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat REFERENCES Campbell, W.C. (1989) Use of ivermectin in clogs and cats. In Ivermectin and Abamectin . Ed. W.C. Campbellpp. 245–259. Springer-Verlag, New York . Clark, J.N., Daurio, C.P., Pitie, R.E., Wallace, D.H. & Longhofer, S.L. (1992) Efficacy of iverniectin antl pyrantel pamioate combined in a chewable formulation against heartworm, hookworm and ascarid infections in dogs. American Journal of Veterinary Research (in press). Daurio. C.P., Cheung, E.N., Jeffcoat, A.K. & Skelly, B.J. (1992) Bioavailability of iverniectin administered oratlly to dogs. Veterinary Research Communications. (In pres). Fink, D.W. & Porras, A.C. (1989) Pharmacokinetics of ivermectin in animals and humans. In Ivermectin and Abamectin . Ed. W.C. Campbellpp. 113–130. Springer-Verlag, New York . Kojima, K., Yamamoto, K., Katae, H. & Nakanishi, Y. (1987) Bioavailability of oral ivermectin in the dog. Nippon Juigaku Zasshi, 49, 899–900. Lo, P-K.A., Fink, D.W., Williams, J.B. & Blodinger, J. (1985) Pharmacokinetic studies of ivermectin: effects of formulation. Veterinary Research Communications, 9, 251–268. McCall, J.W., Dziminanski, M.T. & Plue, R.E. (1986) Ivermectin in heartworm prophylaxis: Studies with experimentally induced and naturally acquired infections. Proceedings of the Heart-worm Sympasium . Ed. G. Ottopp. 9–13. American Heartworm Society, Washington , D.C. . Paul, A.J., Todd, K.S. & Sunberg, J.P. (1986) Efficacy of ivermectin against Dirofilaria immitis larvae in dogs 30 and 45 days after induced infection. American Journal of Veterinary Research, 47, 883–884. Revised Bioequivalence Guidelines (1990). Issued by the Center for Veterinary Medicine, Food and Drug Administration. Citing Literature Volume15, Issue2June 1992Pages 217-220 ReferencesRelatedInformation