Eat Dirt — The Hygiene Hypothesis and Allergic Diseases
2002; Massachusetts Medical Society; Volume: 347; Issue: 12 Linguagem: Inglês
10.1056/nejme020092
ISSN1533-4406
Autores Tópico(s)Eosinophilic Esophagitis
ResumoThere has been an epidemic of both autoimmune diseases (in which the immune response is dominated by type 1 helper T [Th1] cells, such as type 1 diabetes, Crohn's disease, and multiple sclerosis) and allergic diseases (in which the immune response is dominated by type 2 helper T [Th2] cells, such as asthma, allergic rhinitis, and atopic dermatitis), as documented in the article by Bach in this issue of the Journal. 1 The occurrence of these diseases is higher in more affluent, Western, industrialized countries. One theory proposed to explain this increase in the prevalence of autoimmune and allergic diseases is . . .
Referência(s)