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Successful Therapy for Rhinocerebral Mucormycosis With Associated Bilateral Brain Abscesses

1983; American Medical Association; Volume: 143; Issue: 3 Linguagem: Inglês

10.1001/archinte.1983.00350030195037

1538-3679

Richard J. Hamill,

Myasthenia Gravis and Thymoma

A case of extensive rhinocerebral mucormycosis, with associated bilateral brain abscesses, occurred in a man with diabetes. A Rhizopus sp grew from the initial nasal biopsy specimens. Successful therapy consisted of correcting metabolic acidosis, using serial computed tomographic (CT) scans to follow the progressive course of brain involvement from cerebritis to encapsulated abscesses, and performing successive biopsies to determine the adequacy of treatment. On 18-month follow-up, the patient had returned to full-time employment with minimal neurologic impairment. With CT scanning and aggressive therapy, rhinocerebral mucormycosis with bilateral brain involvement can be cured.