Dynamic Guiding of Motor-Driven Microtubules on Electrically Heated, Smart Polymer Tracks
2013; American Chemical Society; Volume: 13; Issue: 7 Linguagem: Inglês
10.1021/nl402004s
ISSN1530-6992
AutoresViktor Schroeder, Till Korten, Heiner Linke, Stefan Diez, Ivan Maximov,
Tópico(s)Advanced Materials and Mechanics
ResumoBiomolecular motor systems are attractive for future nanotechnological devices because they can replace nanofluidics by directed transport. However, the lack of methods to externally control motor-driven transport along complex paths limits their range of applications. Based on a thermo-responsive polymer, we developed a novel technique to guide microtubules propelled by kinesin-1 motors on a planar surface. Using electrically heated gold microstructures, the polymers were locally collapsed, creating dynamically switchable tracks that successfully guided microtubule movement.
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