Successful Treatment of Lymphadenosis benigna cutis with Topical Photodynamic Therapy with Delta-Aminolevulinic Acid
2005; Karger Publishers; Volume: 211; Issue: 3 Linguagem: Inglês
10.1159/000087021
ISSN1421-9832
AutoresHitoshi Takeda, Takahide Kaneko, Ken Harada, Yasushi Matsuzaki, Hajime Nakano, Katsumi Hanada,
Tópico(s)Photodynamic Therapy Research Studies
ResumoPhotodynamic therapy (PDT) using topical delta-aminolevulinic acid (ALA) has been used for nonmelanoma skin cancers, including malignant cutaneous T-cell lymphomas. Moreover, PDT has been tried for benign inflammatory or infectious skin lesions.To evaluate the effects of ALA-PDT on skin lesions of lymphadenosis benigna cutis (LABC).Two 16-year-old females with solitary and infiltrated nodules were treated 5 times with topical ALA-PDT.Both patients responded well and showed dramatic clinical and histopathological improvement without visible scars.The results confirm that topical ALA-PDT is an effective and safe modality for the treatment of LABC, and that such treatment may be cosmetically beneficial.
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