Portal de Periódicos da CAPES

Paraneoplastic hypercalcaemia in ovarian carcinoma.

1984; BMJ; Volume: 288; Issue: 6432 Linguagem: Inglês

10.1136/bmj.288.6432.1714

0959-8138

S.G. Allan, Stephen Lockhart, Renaud Léonard, John F. Smyth,

Bone and Joint Diseases

Five patients were seen in whom a raised serum calcium concentration was associated with ovarian carcinoma (clear cell in two cases, cystadenocarcinoma in three). None showed evidence of metastases in bone. The hypercalcaemia occurred as a paraneoplastic phenomenon, but biochemical studies suggested the production of a parathyroid-hormone-like substance. One patient remained free of symptoms of her hypercalcaemia throughout. Paraneoplastic hypercalcaemia due to ovarian carcinoma may be more common than generally recognised and present as a life threatening condition requiring urgent treatment.