Effects of the chinese herbal medicine “Saiboku-to” on histamine release from and the degranulation of mouse peritoneal mast cells induced by compound
1988; Elsevier BV; Volume: 24; Issue: 2-3 Linguagem: Inglês
10.1016/0378-8741(88)90159-6
ISSN1872-7573
AutoresShizuo Toda, Kimura Michio, Ohnishi Motoyo, Nakashima Kyouzou,
Tópico(s)Pediatric health and respiratory diseases
ResumoThe herbal medicine "Saiboku-to" (ST) has been used for the treatment of bronchial asthma. ST was found to inhibit histamine release from and the degranulation of mouse peritoneal mast cells induced by compound 48/80. Its inhibitory effects were concentration-related and somewhat weaker than disodium cromoglycate, a known inhibitor of histamine release and mast cell degranulation. From these results, ST could appear to be useful in the treatment of Type I allergic reactions.
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