Distribution of magnesium stearate on the surface of lubricated particles
1986; Elsevier BV; Volume: 31; Issue: 1-2 Linguagem: Inglês
10.1016/0378-5173(86)90222-x
ISSN1873-3476
AutoresL. Roblot-Treupel, F. Puisieux,
Tópico(s)Analytical Methods in Pharmaceuticals
ResumoThe distribution of magnesium stearate on the surface of granules is investigated using the scanning electron microscope and microanalysis. The results confirm the preferential location of the stearate in the cavities, and the regularization of the surface provided by the lubricant. Microanalysis of magnesium stearate indicates that a maximum fixation capacity exists.
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