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Invasive Group A Streptococcal Infections, Israel

2002; Centers for Disease Control and Prevention; Volume: 8; Issue: 4 Linguagem: Inglês

10.3201/eid0804.010278

1080-6059

Allon E. Moses, Sara Goldberg, Zinaida Korenman, Miriam Ravins, Emanuel Hanski, Mervyn Shapiro,

Otolaryngology and Infectious Diseases

We conducted a prospective, nationwide, population-based study of invasive group A streptococcal infections in Israel. We identified 409 patients (median age 27 years; range <1-92), for an annual incidence of 3.7/100,000 (11/100,000 in Jerusalem). The mortality rate was 5%. Bacteremia occurred in 125 cases (31%). The most common illnesses were soft-tissue infection (63%) and primary bacteremia (14%). Thirty percent of patients had no identifiable risk factors for infection. Eighty-seven percent of pharyngeal carriers had the same serotype as the index patient. M types included M3 (25%), M28 (10%), and M-nontypable (33%). A marked paucity of M1 serotype (1.2%) was detected. The results highlighted concentrated pockets of invasive disease in the Jewish orthodox community (annual incidence 16/100,000).