Myeloid-Derived Suppressor Cells in Human Cancer
2010; Lippincott Williams & Wilkins; Volume: 16; Issue: 4 Linguagem: Inglês
10.1097/ppo.0b013e3181eb3358
ISSN1540-336X
AutoresSrinivas Nagaraj, Dmitry I. Gabrilovich,
Tópico(s)Macrophage Migration Inhibitory Factor
ResumoMyeloid-derived suppressor cells are one of the major factors responsible for immune suppression in cancer. They also contribute to limited efficacy of current vaccination strategies. Here, we give an overview of the myeloid-derived suppressor cells field focusing primarily on the studies in cancer patients and current and future therapeutic options targeting these cells.
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