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Oligoanthranilamides. Non-Peptide Subunits That Show Formation of Specific Secondary Structure

1996; American Chemical Society; Volume: 118; Issue: 32 Linguagem: Inglês

10.1021/ja9539857

1943-2984

Lora Hamuro, Steven J. Geib, Andrew D. Hamilton,

Click Chemistry and Applications

A family of novel oligomers based on the anthranilamide nucleus has been prepared and shown to form well-defined secondary structural features. 1H NMR and X-ray crystallographic techniques have demonstrated that intramolecular hydrogen bonds play a key role in stabilizing both linear sheet and helical conformational forms.