Voltar
Artigo Revisado por pares
BIBTEX RIS

CTP SYNTHETASE ACTIVITY IN NEONATAL AND ADULT RAT BRAIN

1974; Wiley; Volume: 22; Issue: 6 Linguagem: Inglês

10.1111/j.1471-4159.1974.tb04332.x

ISSN

1471-4159

Autores

Dobri D. Genchev, P. Mandel,

Tópico(s)

RNA modifications and cancer

Resumo

Abstract —The activity of CTP synthetase (UTP:ammonia ligase (ADP‐forming), EC 6.3.4.2) in adult and new‐born rat brain was determined by an enzyme assay using [ 14 C]UTP as a substrate. The activity was age‐dependent and showed a distinctive distribution pattern between the cerebral hemispheres and cerebellum. The possible correlations between the activity of CTP synthetase and the rate of RNA or lipid biosynthesis, as well as the regulatory importance of the enzyme in the formation of cytidine nucleotides are discussed.

Referência(s)