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Multigeneration exposure test ofDrosophila melanogaster to ELF magnetic fields

1998; Wiley; Volume: 19; Issue: 6 Linguagem: Inglês

10.1002/(sici)1521-186x(1998)19

1521-186X

Takehiko Kikuchi, Masahiro Ogawa, Yoshihisa Otaka, Masako Furuta,

Genetics, Aging, and Longevity in Model Organisms

BioelectromagneticsVolume 19, Issue 6 p. 335-340 Multigeneration exposure test of Drosophila melanogaster to ELF magnetic fields Takehiko Kikuchi, Takehiko Kikuchi Engineering Development Center, Tokyo Electric Power Co., Tokyo, JapanSearch for more papers by this authorMasahiro Ogawa, Masahiro Ogawa Engineering Development Center, Tokyo Electric Power Co., Tokyo, JapanSearch for more papers by this authorYoshihisa Otaka, Corresponding Author Yoshihisa Otaka Mitsubishi Kasei Institute of Toxicological and Environmental Sciences, Kashima Laboratory, Ibaraki, JapanMitsubishi Kasei Institute of Toxicological and Environmental Sciences, Sunayama 14, Hasaki-machi, Kashima-gun, Ibaraki 314-02, JapanSearch for more papers by this authorMasako Furuta, Masako Furuta Mitsubishi Kasei Institute of Toxicological and Environmental Sciences, Kashima Laboratory, Ibaraki, JapanSearch for more papers by this author Takehiko Kikuchi, Takehiko Kikuchi Engineering Development Center, Tokyo Electric Power Co., Tokyo, JapanSearch for more papers by this authorMasahiro Ogawa, Masahiro Ogawa Engineering Development Center, Tokyo Electric Power Co., Tokyo, JapanSearch for more papers by this authorYoshihisa Otaka, Corresponding Author Yoshihisa Otaka Mitsubishi Kasei Institute of Toxicological and Environmental Sciences, Kashima Laboratory, Ibaraki, JapanMitsubishi Kasei Institute of Toxicological and Environmental Sciences, Sunayama 14, Hasaki-machi, Kashima-gun, Ibaraki 314-02, JapanSearch for more papers by this authorMasako Furuta, Masako Furuta Mitsubishi Kasei Institute of Toxicological and Environmental Sciences, Kashima Laboratory, Ibaraki, JapanSearch for more papers by this author First published: 06 January 1999 https://doi.org/10.1002/(SICI)1521-186X(1998)19:6 3.0.CO;2-2Citations: 5AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Abstract Mutations, other than dominant lethals, were accumulated on wild type second chromosomes (+) of Drosophila melanogaster during exposure to 50 Hz sinusoidal alternating magnetic fields of 0.5 or 5 mT (rms) for 40 generations by the Curly/Plum(Cy/Pm) accumulation method. We maintained, for 40 generations under continuous exposure, each (+) chromosome as a heterozygote with (Cy) chromosome. Viability of the (+) chromosome was tested by sib-mating of (Cy/+) male and (Cy/+) female in a culture every 10th generation to obtain the homozygote. Viability indices, defined as twice the ratio of number of (+/+) flies to that of (Cy/+) flies plus 1 in the progeny of the test mating, also were calculated, which equaled 1.00 at the starting point. For the control and 0.5 and 5 mT exposed groups, percent frequencies of recessive lethal lines, defined as a line with (+/+) flies less than 0.3% in the test mating, were, respectively, 1.9, 0.9, and 2.9% (10th), 9.0, 4.9, and 9.5% (20th), 30.3, 22.9, and 30.4% (30th), and 39.9, 32.4, and 43.3% (40th generation). For the control and 0.5 and 5 mT groups, average viability indices, excluding lethals and markedly deleterious, were, respectively, 0.778, 0.796, and 0.752 (20th), 0.704, 0.698, and 0.694 (30th), and 0.669, 0.678, and 0.595 (40th generation). Their decreasing rates were 0.0054, 0.0059, and 0.0078 per generation. No significant difference was detected among the exposure levels in either the recessive lethal mutation frequency or the viability index. Bioelectromagnetics 19:335–340, 1998. © 1998 Wiley-Liss, Inc. Citing Literature Volume19, Issue61998Pages 335-340 RelatedInformation