Extraction of major alkaloids from poppy straw with near-critical mixtures of carbon dioxide and polar modifiers
1990; Elsevier BV; Volume: 505; Issue: 1 Linguagem: Inglês
10.1016/s0021-9673(01)93083-3
ISSN1873-3778
AutoresJ.L. Janicot, M. Caude, R. Rosset, Jean‐Luc Veuthey,
Tópico(s)Microfluidic and Capillary Electrophoresis Applications
ResumoNear-critical extraction of major alkaloids from poppy straw was performed successfully with a simple device consisting mainly of two chromatographic pumps and a pressure regulator. The optimum extractant, consisting of carbon dioxide, methanol and water, gave a quantitative extraction of thebaine, codeine and morphine in 20 min. The method was compared with a classical liquid-solid extraction procedure and carbon dioxide was shown to act as a transporting agent of the extraction solvent (methanol-water) into the vegetable matrix.
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