Artigo Revisado por pares

Synthesis, Characterization, and Isomerization of an Iridabenzvalene

2000; Wiley; Volume: 6; Issue: 3 Linguagem: Inglês

10.1002/(sici)1521-3765(20000204)6

ISSN

1521-3765

Autores

Robert D. Gilbertson, T.J.R. Weakley, Michael M. Haley,

Tópico(s)

Cancer Treatment and Pharmacology

Resumo

Metal- halogen exchange of vinylcyclopropene 4 followed by addition of [(Me3P)2Ir(CO)Cl] produced iridabenzvalene 5. The metallabenzene valence isomer was characterized by NMR and IR spectroscopy and by X-ray crystallography. Isomerization of complex 5 to iridabenzene derivatives 6 and 13 was accomplished by thermolysis and by Ag+ ions, respectively. The former transformation was a clean and quantitative process that displayed first-order kinetics.

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