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Occupational Intoxication and Long-Term Persistence of Phencyclidine (PCP) in Law Enforcement Personnel

1981; Informa; Volume: 18; Issue: 9 Linguagem: Inglês

10.3109/15563658108990331

0009-9309

Ferris N. Pitts, Robert E. Allen, Orm Aniline, Lane S. Yago,

Carcinogens and Genotoxicity Assessment

AbstractBy utilizing a glass capillary gas chromatographic nitrogen detector (GC2-N) method specific for phencyclidine (PCP) and sensitive to pg/mL in blood or urine samples, we have demonstrated occupational intoxication of law enforcement personnel charged with handling confiscated illegal PCP preparations. Further, we have demonstrated persistence of PCP in blood and urine for at least 6 months after the last known occupational exposure in one officer. Some aspects of the PCP problem are outlined, and possible mechanisms of the occupational intoxication are discussed.