Chicken lens development: Epithelial cell production and migration
1966; Elsevier BV; Volume: 5; Issue: 2 Linguagem: Inglês
10.1016/s0014-4835(66)80027-1
ISSN1096-0007
AutoresCalvin Hanna, Henry C. Keatts,
Tópico(s)Connexins and lens biology
ResumoIn the earliest stages of chicken lens development, cell division occurred over the entire lens. Cell division first stopped in the posterior side of the lens vesicle, as the cells differentiated into primary lens fibers. After the annular pad developed, cell division occurred, for the most part, in the anterior surface epithelial cells. Shortly after hatching and thereafter, a germinative zone, consisting of a narrow band of epithelial cells adjacent to the annular pad developed. The cells from the germinative zone migrated slowly and differentiated first into annular pad cells and then into lens cortex fibers over an estimated 2-year period. This slow migration of cells in the lens is discussed in relation to the failure of the adult chicken to develop radiation cataracts.
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