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Hormonal Regulation of Lipolysis: Role of Cyclic Nucleotides, Adenosine, and Free Fatty Acids

1979; Springer Nature; Linguagem: Inglês

10.1007/978-1-4757-0734-2_3

2214-8019

John N. Fain, R. E. Shepherd,

Muscle metabolism and nutrition

Twenty years ago, Dole (1956) and Gordon and Cherkes (1956) presented evidence that lipid is mobilized from adipose tissue in the form of free fatty acids noncovalently bound to plasma albumin. The fatty acids are taken up by muscle, liver, and other tissues where they are either oxidized as a source of energy or reesterified. In addition, free fatty acids (FFA) may also be converted to ketone bodies by liver and, subsequently, oxidized by muscle and the brain as a source of energy.