Generation of thymus-derived helper cells by macrophage-associated antigen
1974; Elsevier BV; Volume: 10; Issue: 3 Linguagem: Inglês
10.1016/0008-8749(74)90140-3
ISSN1090-2163
Autores Tópico(s)Immunotherapy and Immune Responses
ResumoA double cell transfer system was used to investigate the efficacy of macrophage bound antigen in generating carrier-reactive helper T cells. Macrophage bound antigen was found to be three orders of magnitude more potent than soluble antigen in T cell priming. The results are discussed with reference to the involvement of macrophages or related cells in the normal processes of immune induction.
Referência(s)