Alkoxy radicals in organic synthesis. A novel approach to a key intermediate in milbemycin chemistry
1994; Elsevier BV; Volume: 35; Issue: 28 Linguagem: Inglês
10.1016/s0040-4039(00)73322-3
ISSN1873-3581
AutoresNigel Hussain, David O. Morgan, Charles R. White, John A. Murphy,
Tópico(s)Asymmetric Synthesis and Catalysis
ResumoThe fragmentation of nitrate ester (2) via an alkoxy radical to lactone (3) is described. This lactone is a key intermediate in the synthesis of semisynthetic milbemycins.
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