Stimulation of gonadotropin secretion by intraventricular injection of hypothalamic extracts in the goldfish, Carassius auratus
1976; Elsevier BV; Volume: 30; Issue: 1 Linguagem: Inglês
10.1016/0016-6480(76)90068-x
ISSN1095-6840
AutoresL.W. Crim, Richard Peter, Roland Billard,
Tópico(s)Sperm and Testicular Function
ResumoGoldfish serum gonadotropin (GTH) concentrations were determined by radioimmunoassay 20 min after injection of goldfish brain extracts or synthetic luteinizing hormone-releasing hormone (LH-RH) into the third ventricle in the ventrobasal hypothalamic region. Extracts of the cerebellum and medulla were ineffective. Synthetic LH-RH, and extract of the lateral hypothalamus each significantly increased plasma GTH levels. The results indicate that the hypothalamus of the sexually mature female goldfish contains gonadotropin releasing hormone activity, and that releasing hormone is effective when administered via the intrahypothalamic route.
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