Revisão Revisado por pares

How I treat heparin-induced thrombocytopenia and thrombosis

2002; Elsevier BV; Volume: 101; Issue: 1 Linguagem: Inglês

10.1182/blood-2002-04-1089

ISSN

1528-0020

Autores

Barbara M. Alving,

Tópico(s)

Venous Thromboembolism Diagnosis and Management

Resumo

Heparin-induced thrombocytopenia (HIT) is one of the most common and potentially devastating of immune-mediated drug reactions.[1][1] The clinical manifestations of this disorder are initiated by antibodies directed against platelet factor 4 (PF4), which becomes an antigenic target when bound to

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