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Enhancing the Toxicity of Cancer Chemotherapeutics with Gold Nanorod Hyperthermia

2008; Volume: 20; Issue: 20 Linguagem: Inglês

10.1002/adma.200800921

1521-4095

Tanya S. Hauck, Travis L. Jennings, Tetyana Yatsenko, J. Carl Kumaradas, Warren C. W. Chan,

Nanoplatforms for cancer theranostics

Advanced MaterialsVolume 20, Issue 20 p. 3832-3838 Communication Enhancing the Toxicity of Cancer Chemotherapeutics with Gold Nanorod Hyperthermia† Tanya S. Hauck, Tanya S. Hauck Institute of Biomaterials and Biomedical Engineering, Materials Science and Engineering, Chemical Engineering and Applied Chemistry Terrence Donnelly Center for Cellular and Biomolecular Research University of Toronto 160 College Street, 4th Floor, Toronto, ON M5S 3G9 (Canada)Search for more papers by this authorTravis L. Jennings, Travis L. Jennings Institute of Biomaterials and Biomedical Engineering, Materials Science and Engineering, Chemical Engineering and Applied Chemistry Terrence Donnelly Center for Cellular and Biomolecular Research University of Toronto 160 College Street, 4th Floor, Toronto, ON M5S 3G9 (Canada)Search for more papers by this authorTetyana Yatsenko, Tetyana Yatsenko Department of Physics Ryerson University 350 Victoria Street, Toronto, ON M5B 2K3 (Canada)Search for more papers by this authorJ. Carl Kumaradas, J. Carl Kumaradas Department of Physics Ryerson University 350 Victoria Street, Toronto, ON M5B 2K3 (Canada)Search for more papers by this authorWarren C. W. Chan, Corresponding Author Warren C. W. Chan [email protected] Institute of Biomaterials and Biomedical Engineering, Materials Science and Engineering, Chemical Engineering and Applied Chemistry Terrence Donnelly Center for Cellular and Biomolecular Research University of Toronto 160 College Street, 4th Floor, Toronto, ON M5S 3G9 (Canada)Institute of Biomaterials and Biomedical Engineering, Materials Science and Engineering, Chemical Engineering and Applied Chemistry Terrence Donnelly Center for Cellular and Biomolecular Research University of Toronto 160 College Street, 4th Floor, Toronto, ON M5S 3G9 (Canada).Search for more papers by this author Tanya S. Hauck, Tanya S. Hauck Institute of Biomaterials and Biomedical Engineering, Materials Science and Engineering, Chemical Engineering and Applied Chemistry Terrence Donnelly Center for Cellular and Biomolecular Research University of Toronto 160 College Street, 4th Floor, Toronto, ON M5S 3G9 (Canada)Search for more papers by this authorTravis L. Jennings, Travis L. Jennings Institute of Biomaterials and Biomedical Engineering, Materials Science and Engineering, Chemical Engineering and Applied Chemistry Terrence Donnelly Center for Cellular and Biomolecular Research University of Toronto 160 College Street, 4th Floor, Toronto, ON M5S 3G9 (Canada)Search for more papers by this authorTetyana Yatsenko, Tetyana Yatsenko Department of Physics Ryerson University 350 Victoria Street, Toronto, ON M5B 2K3 (Canada)Search for more papers by this authorJ. Carl Kumaradas, J. Carl Kumaradas Department of Physics Ryerson University 350 Victoria Street, Toronto, ON M5B 2K3 (Canada)Search for more papers by this authorWarren C. W. Chan, Corresponding Author Warren C. W. Chan [email protected] Institute of Biomaterials and Biomedical Engineering, Materials Science and Engineering, Chemical Engineering and Applied Chemistry Terrence Donnelly Center for Cellular and Biomolecular Research University of Toronto 160 College Street, 4th Floor, Toronto, ON M5S 3G9 (Canada)Institute of Biomaterials and Biomedical Engineering, Materials Science and Engineering, Chemical Engineering and Applied Chemistry Terrence Donnelly Center for Cellular and Biomolecular Research University of Toronto 160 College Street, 4th Floor, Toronto, ON M5S 3G9 (Canada).Search for more papers by this author First published: 17 October 2008 https://doi.org/10.1002/adma.200800921Citations: 337 † This project was financially supported by CIHR, NSERC, CFI, and OIT. We gratefully thank Dr. Chen Wang at Mt. Sinai Hospital for the OCI AML3 cells and Dr. Aaron Wheeler's laboratory (Univ. of Toronto) for the Jurkat T-Cells. The authors also thank Dionne White for help with flow cytometry and gratefully acknowledge the J. E. Davies laboratory (Univ. of Toronto) for use of their ViCell, the M. V. Sefton laboratory (Univ. of Toronto) for the use of their incubator, and Dr. William M. Whelan (Ryerson University) for use of his laser. T.H. thanks NSERC, CFUW, and the K. M. Hunter Foundation for funding. Supporting Information is available online from Wiley InterScience or from the authors. AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat Graphical Abstract The heat produced by optically excited gold nanorods is used to augment the chemotherapeutic agent cisplatin in killing tumor cells. This combined therapy kills 78% more cells than cisplatin alone, suggesting a synergistic interaction between these treatments. Supporting Information Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Filename Description adma_200800921_sm_miscellaneous_information.pdf1.2 MB miscellaneous information Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article. References 1 M. Ferrari, Nat. Rev. Cancer 2005, 5, 161. 2 N. W. Kam, M. O'Connell, J. A. Wisdom, H. Dai, Proc. Natl. Acad. Sci. USA 2005, 102, 11600. 3 L. Hirsch, R. Stafford, J. Bankson, S. Sershen, B. Rivera, R. Price, J. Hazle, N. Halas, J. West, Proc. Natl. Acad. Sci. USA 2003, 100, 13549. 4 A. M. Gobin, M. H. Lee, N. J. Halas, W. D. James, R. A. Drezek, J. L. West, Nano Lett. 2007, 7, 1929. 5 X. Huang, I. El-Sayed, W. Qian, M. El-Sayed, J. Am. Ceram. Soc. 2006, 128, 2115. 6 P. E. Kintzel, R. T. Dorr, Cancer Treat. Rev. 1995, 21, 33. 7 S. Jaracz, J. Chen, L. V. Kuznetsova, I. Ojima, Bioorg. Med. Chem. 2005, 13, 5043. 8 K. J. Schimmel, D. J. Richel, R. B. van den Brink, H. J. Guchelaar, Cancer Treat. Rev. 2004, 30, 181. 9 M. A. Moses, H. Brem, R. Langer, Cancer Cell 2003, 4, 337. 10 G. Los, P. Sminia, J. Wondergem, P. H. Mutsaers, J. Havemen, D. ten Bokkel Huinink, O. Smals, D. Gonzalez-Gonzalez, J. G. McVie, Eur. J. Cancer 1991, 27, 472. 11 S. Ohno, Z. H. Siddik, Y. Kido, L. A. Zwelling, J. M. Bull, Cancer Chemother. Pharmacol. 1994, 34, 302. 12 O. Dahl, in Thermoradiotherapy and Thermochemotherapy, Vol. 1(Eds: M. Seegenschmiedt, P Fessenden, C. Vernon), Springer, Berlin 1995, p. 103. 13 O. Dahl, in Hyperthermia (Eds: D. Watmough, W. Ross), Blackie, Glasgow 1986, p. 121. 14 F. Hetzel, J. Mattiello, in Biological, Physical and Clinical Aspects of Hyperthermia (Eds: B. Paliwal, F Hetzel, M. Dewhirst), AIP, New York 1987, p. 30. 15 A. M. Westermann, E. L. Jones, B. C. Schem, E. M. van der Steen-Banasik, P. Koper, O. Mella, A. L. Uitterhoeve, R. de Wit, J. van der Velden, C. Burger, C. L. van der Wilt, O. Dahl, L. R. Prosnitz, J. van der Zee, Cancer 2005, 104, 763. 16 R. Issels, in Thermoradiotherapy and Thermochemotherapy, Vol. II (Eds: M. Seegenschmiedt, P Fessenden, C. Vernon), Springer, Berlin 1995, p. 25. 17 D. Coffey, R. Getzenberg, T. DeWeese, J. Am. Med. Assoc. 2006, 296, 445. 18 G. M. Hahn, J. Braun, I. Har-Kedar, Proc. Natl. Acad. Sci. USA 1975, 72, 937. 19 J. Strohbehn, in Hyperthermia in Cancer Treatment Vol. II (Eds: L. Anghileri, J. Robert), CRC Press, Boca Raton, FL, 1986, pp. 179. 20 J. Meyer, D. Kapp, P. Fessenden, G. Hahn, Pharm. Ther. 1989, 42, 251. 21 P. Wust, B. Hildebrandt, G. Sreenivasa, B. Rau, J. Gellermann, H. Riess, R. Felix, P. Schlag, Lancet Oncol. 2002, 3, 487. 22 K. König, J. Microsc. 2000, 200, 83. 23 L. Tong, Y. Zhao, T. B. Huff, M. N. Hansen, A. Wei, J. X. Cheng, Adv. Mater. 2007, 19, 3136. 24 S. Link, M. El-Sayed, J. Phys. Chem. B 1999, 103, 8410. 25 P. K. Jain, K. S. Lee, I. H. El-Sayed, M. A. El-Sayed, J. Phys. Chem. B 2006, 110, 7238. 26 T. S. Hauck, A. A. Ghazani, W. C. W. Chan, Small 2008, 4, 153. 27 B. Chithrani, A. Ghazani, W. C. W. Chan, Nano Lett. 2006, 6, 662. 28 B. Chithrani, W. C. W. Chan, Nano Lett. 2007, 7, 1542. 29 W. Jiang, B. Y. S. Kim, J. T. Rutka, W. C. W. Chan, Nat. Nanotechnol. 2008, 3, 145. 30 L. Stuart, R. A. Ezekowitz, Immunity 2005, 22, 539. 31 A. August, S. Gibson, Y. Kawakami, T. Kawakami, G. B. Mills, B. Dupont, Proc. Natl. Acad. Sci. USA 1994, 91, 9347. 32 G. Hahn, Hyperthermia and Cancer, Plenum, New York 1982. 33 B. Hildebrandt, P. Wust, O. Ahlers, A. Dieing, G. Sreenivasa, T. Kerner, R. Felix, H. Riess, Crit. Rev. Oncol. Hematol. 2002, 43, 33. 34 E. Gabano, D. Colangelo, A. R. Ghezzi, D. Osella, J. Inorg. Biochem. 2007, 98, 73. 35 A. Felici, J. Verweij, A. Sparreboom, Eur. J. Cancer 2002, 38, 1677. 36 S. Sershen, S. Westcott, N. Halas, J. West, J. Biomed. Mater. Res. 2000, 51, 293. 37 A. Rösler, G. Vandermeulen, H.-A. Klok, Adv. Drug Delivery Rev. 2001, 53, 95. 38 C. J. Murphy, T. K. Sau, A. M. Gole, C. J. Orendorff, J. Gao, L. Gou, S. E. Hunyadi, T. Li, J. Phys. Chem. B 2005, 109, 13857. 39 J. Pérez-Juste, M. A. Correa-Duarte, L. M. Liz-Marzán, Appl. Surf. Sci. 2003, 226, 137. Citing Literature Volume20, Issue20October 17, 2008Pages 3832-3838 ReferencesRelatedInformation