Effect of Formalin Fixation on the Activity of Five Enzymes of Rat Liver
1951; Taylor & Francis; Volume: 26; Issue: 1 Linguagem: Inglês
10.3109/10520295109113172
ISSN0038-9153
AutoresArnold M. Seligman, Howard H. Chauncey, Marvin M. Nachlas,
Tópico(s)Biopolymer Synthesis and Applications
ResumoAbstractThe effect of formalin fixation on the enzymatic activity of five enzymes in rat liver was studied as a function of time and temperature, β-glucuronidase was found to be most resistant to the inactivating effects of formalin. At a time when fixation was satisfactory for preparing frozen sections (24 hours), considerable enzymatic activity was present in decreasing order; β-glucuronidase, sulfatase, acid phosphatase, esterase, and alkaline phosphatase.
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