Relationship of Plasma Level of Vitamin C to Mortality from Ischemic Heart Disease
1987; Wiley; Volume: 498; Issue: 1 Linguagem: Inglês
10.1111/j.1749-6632.1987.tb23755.x
ISSN1749-6632
AutoresK.F. Gey, Hannes B. Stähelin, Pekka Puska, Alun Evans,
Tópico(s)Pharmacological Effects of Natural Compounds
ResumoAnnals of the New York Academy of SciencesVolume 498, Issue 1 p. 110-123 Relationship of Plasma Level of Vitamin C to Mortality from Ischemic Heart Disease K. FRED GEY, K. FRED GEY Vitamin Research Department F. Hoffmann-La Roche & Co., Ltd. Basel, Switzerland In experimental collaboration with Flaminio Fidanza, Perugia, Italy; Horst Georgi, Basel, Switzerland; Mario Mancini, Naples, Italy; Tapio Nikkari, Tampere, Finland; Michael F. Oliver, Edinburgh, Scotland; Rudolph A. Riemersma, Edinburgh, Scotland; Günther Ritzel, Basel, Switzerland; Paolo Rubba, Naples, Italy; Matti Salo, Tampere, Finland; Erkki Vartiainen, Helsinki, Finland; Jean Paul Vuilleumier, Basel, Switzerland; and David A. Wood, Edinburgh, Scotland, as principal investigators of the International Collaborative Study on the Fatty Acid-Antioxidant Hypothesis of Arteriosclerosis. Optional Study on Antioxidant Vitamins, WHO-MONICA Project.Search for more papers by this authorHANNES B. STÄHELIN, HANNES B. STÄHELIN Geriatric Clinic Kantonsspital University of Basel Basel, Switzerland On behalf of the prospective Basel Study, with Georg B. Brubacher, Hans Riggenbach, Florence Bernasconi, and Jean Paul Vuilleumier of F. Hoffmann-La Roche & Co., Ltd., Basel, Switzerland, as co-workers.Search for more papers by this authorPEKKA PUSKA, PEKKA PUSKA Public Health Institute Helsinki, Finland In experimental collaboration with Flaminio Fidanza, Perugia, Italy; Horst Georgi, Basel, Switzerland; Mario Mancini, Naples, Italy; Tapio Nikkari, Tampere, Finland; Michael F. Oliver, Edinburgh, Scotland; Rudolph A. Riemersma, Edinburgh, Scotland; Günther Ritzel, Basel, Switzerland; Paolo Rubba, Naples, Italy; Matti Salo, Tampere, Finland; Erkki Vartiainen, Helsinki, Finland; Jean Paul Vuilleumier, Basel, Switzerland; and David A. Wood, Edinburgh, Scotland, as principal investigators of the International Collaborative Study on the Fatty Acid-Antioxidant Hypothesis of Arteriosclerosis. Optional Study on Antioxidant Vitamins, WHO-MONICA Project.Search for more papers by this authorALUN EVANS, ALUN EVANS World Health Organization MONICA Center Belfast, Northern Ireland Optional Study on Antioxidant Vitamins, WHO-MONICA Project.Search for more papers by this author K. FRED GEY, K. FRED GEY Vitamin Research Department F. Hoffmann-La Roche & Co., Ltd. Basel, Switzerland In experimental collaboration with Flaminio Fidanza, Perugia, Italy; Horst Georgi, Basel, Switzerland; Mario Mancini, Naples, Italy; Tapio Nikkari, Tampere, Finland; Michael F. Oliver, Edinburgh, Scotland; Rudolph A. Riemersma, Edinburgh, Scotland; Günther Ritzel, Basel, Switzerland; Paolo Rubba, Naples, Italy; Matti Salo, Tampere, Finland; Erkki Vartiainen, Helsinki, Finland; Jean Paul Vuilleumier, Basel, Switzerland; and David A. Wood, Edinburgh, Scotland, as principal investigators of the International Collaborative Study on the Fatty Acid-Antioxidant Hypothesis of Arteriosclerosis. Optional Study on Antioxidant Vitamins, WHO-MONICA Project.Search for more papers by this authorHANNES B. STÄHELIN, HANNES B. STÄHELIN Geriatric Clinic Kantonsspital University of Basel Basel, Switzerland On behalf of the prospective Basel Study, with Georg B. Brubacher, Hans Riggenbach, Florence Bernasconi, and Jean Paul Vuilleumier of F. Hoffmann-La Roche & Co., Ltd., Basel, Switzerland, as co-workers.Search for more papers by this authorPEKKA PUSKA, PEKKA PUSKA Public Health Institute Helsinki, Finland In experimental collaboration with Flaminio Fidanza, Perugia, Italy; Horst Georgi, Basel, Switzerland; Mario Mancini, Naples, Italy; Tapio Nikkari, Tampere, Finland; Michael F. Oliver, Edinburgh, Scotland; Rudolph A. Riemersma, Edinburgh, Scotland; Günther Ritzel, Basel, Switzerland; Paolo Rubba, Naples, Italy; Matti Salo, Tampere, Finland; Erkki Vartiainen, Helsinki, Finland; Jean Paul Vuilleumier, Basel, Switzerland; and David A. Wood, Edinburgh, Scotland, as principal investigators of the International Collaborative Study on the Fatty Acid-Antioxidant Hypothesis of Arteriosclerosis. Optional Study on Antioxidant Vitamins, WHO-MONICA Project.Search for more papers by this authorALUN EVANS, ALUN EVANS World Health Organization MONICA Center Belfast, Northern Ireland Optional Study on Antioxidant Vitamins, WHO-MONICA Project.Search for more papers by this author First published: July 1987 https://doi.org/10.1111/j.1749-6632.1987.tb23755.xCitations: 73 In experimental collaboration with Flaminio Fidanza, Perugia, Italy; Horst Georgi, Basel, Switzerland; Mario Mancini, Naples, Italy; Tapio Nikkari, Tampere, Finland; Michael F. Oliver, Edinburgh, Scotland; Rudolph A. Riemersma, Edinburgh, Scotland; Günther Ritzel, Basel, Switzerland; Paolo Rubba, Naples, Italy; Matti Salo, Tampere, Finland; Erkki Vartiainen, Helsinki, Finland; Jean Paul Vuilleumier, Basel, Switzerland; and David A. Wood, Edinburgh, Scotland, as principal investigators of the International Collaborative Study on the Fatty Acid-Antioxidant Hypothesis of Arteriosclerosis. AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat REFERENCES 1 Gey, K. F. 1986. On the antioxidant hypothesis with regard to arteriosclerosis. Bibl. Nutr. Dieta 37: 53–91. 2 Slater, T. F. 1976. Panminerva Medica 18: 381–390. 3 Vartiainen, E., P. Puska, J. Huttunen, H. Karppanen & K. F. Gey. 1983. Vitamiinit ja sepelvattimotauti. Finn. Med. J. 35: 3146–3150. 4 Riemersma, R. A., D. A. Wood, S. Butler, R. A. Elton, M. Oliver, M. Salo, T. Nikkari, E. Vartiainen, P. Puska, K. F. Gey, P. Rubba, M. Mancini & F. Fidanza. 1986. Linoleic acid content in adipose tissue and coronary heart disease. Brit. Med. J. 292: 1423–1427. 5 Gey, K. F., H. B. Stähelin, G. B. Brubacher, H. Riggenbach, F. Bernasconi & L. K. Widmer. 1987. Inverse association of antioxidant vitamins in plasma with subsequent risk of cancer. Initial level of vitamins A, C, E and β-carotene in 2975 men followed-up for 7 years in the prospective Basel Study. Submitted. 6 Stähelin, H. B., K. F. Gey & G. B. Brubacher. 1987. Plasma vitamin C and cancer death. This volume. 7 Bureau OF Nutritional Sciences, Department OF National Health AND Welfare, Canada. 1983. Recommended nutrient intake for Canadians. Canadian Government Publications Centre pp. 64–76. 8 Machlin, L. J. Vitamin E. 1984. In Handbook of Vitamins. L. J. Machlin Ed.: 99–145. Dekker. New York and Basel . 9 Kok, F. J., A. M. De Eb, R. Vermeeren, A. Hofman, A. Van Laar, M. De Bruin, R. J. J. Hermus & H. A. Valkenburg. 1986. Serum selenium, vitamin antioxidants and cardiovascular mortality. A 9-year follow-up study in the Netherlands. Am. J. Epidemiol. In press. 10 Niki, E. 1987. Interaction of ascorbate and α-tocopherol. This volume. 11 Willson, R. L. 1983. Free radical protection: Why vitamin E, not vitamin C, β-carotene or glutathione? In Ciba Foundation Symposium 101. Pitman. London pp. 19–37. 12 Buzina, R., J. Aurer-Kozelj, K. Srdak-Jorgic, E. Bühler & K. F. Gey. 1987. Increase of gingival hydroxyproline and proline by improvement of ascorbic acid status in man. Int. J. Vit. Nutr. Res. 56: 367–372. 13 Schwarz, R. I., P. Kleinman & N. Owens. 1987. Ascorbate can act as an inducer of the collagen pathway because most steps are tightly coupled. This volume. 14 Ginter, E., M. Jurčovičová & J. Jurcoviciva. 1987. Chronic vitamin C deficiency lowers fractional catabolic rate of low-density lipoproteins (LDL) in guinea pigs. This volume. 15 Jacques, P. F., S. C. Hartz, R. B. McGandy, R. A. Jacob & R. M. Russell. 1987. Vitamin C and blood lipoproteins in an elderly population. This volume. 16 Moser, U. 1987. Uptake of ascorbic acid by leukocytes. This volume. Citing Literature Volume498, Issue1Third Conference on Vitamin CJuly 1987Pages 110-123 ReferencesRelatedInformation
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