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Influence of Age on Susceptibility to Liver Carcinogenesis and Skin Initiating Action by Urethane in Swiss Mice

1963; Springer Nature; Volume: 17; Issue: 4 Linguagem: Inglês

10.1038/bjc.1963.85

1532-1827

Luigi Chieco‐Bianchi, Giuseppe De Benedictis, Giuseppe Tridente, L Fiore-Donati,

Biochemical Analysis and Sensing Techniques

IN recent years development of tumours in different organs of mice following administration of urethane (ethyl carbamate) has been reported by several investigators.In addition to the carcinogenic action on lung tissue, known since the early work of Nettleship and Henshaw (1943), urethane has recently been found to have an initiating action in skin carcinogenesis (Salaman and Roe, 1953;