Observations on the Symptomatic Treatment of Chronic Vascular Headache with Cafergone (Ergotamine Tartrate and Caffeine)
1949; Massachusetts Medical Society; Volume: 241; Issue: 23 Linguagem: Inglês
10.1056/nejm194912082412303
ISSN1533-4406
AutoresSheldon G. Cohen, Leo H. Criep,
Tópico(s)Migraine and Headache Studies
ResumoTHE migrainous patient is grateful for any medication that will afford him symptomatic relief. Until recently, about the only medication capable of offering him any appreciable degree of comfort was ergotamine tartrate. Within the past year, a new preparation, Cafergone,§ has become available. This product contains a combination of ergotamine tartrate and caffeine.Ergotamine is a natural alkaloid derived from ergot, a fungus found growing upon rye and other grains. Its pharmacologic actions1 in man can be briefly outlined as follows: increase in contractions of the uterus by direct stimulation of the uterine musculature; constriction of smaller blood vessels, which . . .
Referência(s)