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From Culture to Vaccine — Salk and Sabin

2004; Massachusetts Medical Society; Volume: 351; Issue: 15 Linguagem: Inglês

10.1056/nejmp048217

1533-4406

Samuel L. Katz,

T-cell and Retrovirus Studies

The Nobel Prize–winning demonstration by John Enders, Frederick Robbins, and Thomas Weller that polioviruses could be propagated successfully in nonneural cell cultures paved the way for two brilliant, ambitious scientists to reorient and accelerate their development of poliovirus vaccines. The backgrounds of Jonas Salk (Figure) and Albert Sabin (Figure) were similar in many ways. Salk was born in New York City, the eldest son of an Orthodox Jewish designer of blouses in Manhattan's garment district. He was a superb student who made his way through a special high school for honors students, on to City College where he . . .