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AN IMPROVED SYNTHESIS OF N-[(9-HYDROXYMETHYL)-2-FLUORENYL]SUCCINAMIC ACID (HMFS), A VERSATILE HANDLE FOR THE SOLID-PHASE SYNTHESIS OF BIOMOLECULES

2001; Taylor & Francis; Volume: 31; Issue: 2 Linguagem: Inglês

10.1081/scc-100000203

1532-2432

Fernando Alberício, Montse Cruz, Laurent Debéthune, Ramón Eritja, Ernest Giralt, Anna Grandas, Vicente Marchán, José J. Pastor, Enrique Pedroso, Francesc Rabanal, Míriam Royo,

Advanced biosensing and bioanalysis techniques

The optimization of a synthetic process for the preparation of HMFS handle, which is used for the solid-phase synthesis of peptides and oligonucleotides, is presented.