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Radioiodinated lymphocyte surface glycoproteins: Concanavalin a binding proteins include surface immonoglobulin

1974; Elsevier BV; Volume: 61; Issue: 4 Linguagem: Inglês

10.1016/s0006-291x(74)80415-8

1090-2104

Susan M. Hunt, John J. Marchalonis,

Erythrocyte Function and Pathophysiology

125I-labelled membrane glycoproteins binding to Concanavalin A were isolated from detergent solubilized mouse lymphocytes which had been surface radioiodinated using lactoperoxidase. Major components with apparent molecular weights of 120,000; 73,000; 40,000; 34,000; 27,000 and 23,000 were obtained. IgM immunoglobulin constituted a minor glycoprotein component. Two μ-like heavy chains differing in carbohydrate were present in this surface immunoglobulin.