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The expulsion of Aspiculuris tetraptera and syphacia spp. from mice after anthelmintic treatment

1980; Elsevier BV; Volume: 10; Issue: 3 Linguagem: Inglês

10.1016/0020-7519(80)90050-8

1879-0135

John C.W. Comley,

Insect Utilization and Effects

The expulsion of Aspiculuris tetraptera and Syphacia spp. from mice after anthelmintic treatment. International Journal for Parasitology10: 205–211. The effect of four benzimidazoles, piperazine and levamisole on the expulsion of adult Aspiculuris tetraptera and Syphacia spp. from mice is described on a quantitative basis. Levamisole and piperazine were found to initiate expulsion within a few hours, but this ceased by 24 h. Following benzimidazole treatment most pinworms were expelled between 24 and 48 h. Syphacia spp. responded earlier to the benzimidazoles than did A. tetraptera, but later to levamisole; both species responded similarly to piperazine. Only levamisole and mebendazole were completely effective against both species within 24 h, piperazine being the least effective. The in vitro effects of levamisole on the motility and the recovery from drug-induced paralysis of the same nematode species are also reported.