Radiologic Features of Vasculitis Involving the Gastrointestinal Tract
2000; Radiological Society of North America; Volume: 20; Issue: 3 Linguagem: Inglês
10.1148/radiographics.20.3.g00mc02779
ISSN1527-1323
AutoresHyun Kwon Ha, Seung Hwan Lee, Sung Eun Rha, Jee-H. Kim, Jae Young Byun, Hyo Keun Lim, Jin Wook Chung, Jeong G. Kim, Pyo Nyun Kim, M.-W. Lee, Yong Ho Auh,
Tópico(s)IgG4-Related and Inflammatory Diseases
ResumoVasculitides can cause local or diffuse pathologic changes in the gastrointestinal tract, resulting in nonspecific paralytic ileus, mesenteric ischemia, submucosal edema and hemorrhage, or bowel perforation or stricture. The extent and clinical course of disease depend on the size and location of the affected vessel and the histologic characteristics of the lesion. Vasculitis may primarily involve large vessels (eg, giant cell arteritis, Takayasu arteritis), medium-sized vessels (eg, polyarteritis nodosa, Kawasaki disease, primary granulomatous central nervous system vasculitis), or small vessels (eg, Wegener granulomatosis, Churg-Strauss syndrome, microscopic polyangiitis, Henoch-Schönlein syndrome, systemic lupus erythematosus, rheumatoid vasculitis, Behçet syndrome). Radiologic findings in various types of vasculitis often overlap considerably and therefore have limited value in making a specific diagnosis. Nevertheless, the possibility of vasculitis should be considered whenever mesenteric ischemic changes occur in young patients, are noted at unusual sites (eg, stomach, duodenum, rectum), have a tendency to concomitantly involve the small and large intestine, and are associated with genitourinary involvement. Knowledge of systemic clinical manifestations in affected patients may suggest and even help establish the specific diagnosis.
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