Inhibitory effect of soybean hypocotyls on Epstein–Barr virus early antigen induction and skin tumor promotion
1997; Elsevier BV; Volume: 121; Issue: 1 Linguagem: Inglês
10.1016/s0304-3835(97)00335-2
ISSN1872-7980
AutoresYukihiro Zaizen, Harukuni Tokuda, Hoyoku Nishino, Masazumi Takeshita,
Tópico(s)Polysaccharides and Plant Cell Walls
ResumoThe in vitro anti-tumor promoting effect of hypocotyls from fresh soybeans was evaluated. The dimethyl sulfoxide extracts of hypocotyls showed a stronger inhibitory effect than that of soybeans on Epstein-Barr virus early antigen activation induced by 12-O-tetradecanoylphorbol-13-acetate. Daidzin, an isoflavone with the highest content of hypocotyls, was also inhibitory. An in vivo evaluation of anti-tumor promoting activity of hypocotyls against the skin of mice also revealed a significant inhibitory effect on tumor formation.
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