Strategies for targeting therapeutic gene delivery
1999; Elsevier BV; Volume: 5; Issue: 10 Linguagem: Inglês
10.1016/s1357-4310(99)01579-8
ISSN1878-4178
Autores Tópico(s)Viral Infectious Diseases and Gene Expression in Insects
ResumoA major goal for gene therapy is to obtain targeted vectors that transfer genes efficiently to specific cell types. In theory, this can be achieved by targeting entry of the vector or by building gene expression cassettes that restrict gene expression to certain cell types. This review summarizes recent strategies to alter vector tropism for targeted gene delivery.
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