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Vasectomy and the Risk of Prostate Cancer

2008; Lippincott Williams & Wilkins; Volume: 180; Issue: 6 Linguagem: Inglês

10.1016/j.juro.2008.08.042

1527-3792

Sarah K. Holt, Claudia A. Salinas, Janet L. Stanford,

Sexual function and dysfunction studies

No AccessJournal of UrologyAdult Urology1 Dec 2008Vasectomy and the Risk of Prostate Cancer Sarah K. Holt, Claudia A. Salinas, and Janet L. Stanford Sarah K. HoltSarah K. Holt Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington , Claudia A. SalinasClaudia A. Salinas Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington Department of Epidemiology, University of Washington, Seattle, Washington , and Janet L. StanfordJanet L. Stanford Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington Department of Epidemiology, University of Washington, Seattle, Washington View All Author Informationhttps://doi.org/10.1016/j.juro.2008.08.042AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: While the weight of evidence shows no association overall between vasectomy and prostate cancer, there has been some suggestion that an association may exist in subgroups, such as men who have a family history of prostate cancer, men who undergo vasectomy at a younger age or when several decades have passed since the procedure. Studies of risk with long latency periods have been hampered by small sample sizes in subgroups since vasectomy only became widely used in the 1960s and generally prostate cancer has a long latency period. Materials and Methods: We analyzed data from a recent population based case-control study that was designed specifically to address this issue of risk in subgroups. Interviews were completed with 1,001 men diagnosed with prostate cancer from January 1, 2002 through December 31, 2005 in the Seattle-Puget Sound region and in 942 matched control men. Subjects were black and white men between the ages of 35 and 74 years. Data were analyzed using unconditional logistic regression to calculate the OR as an estimate of the relative risk of prostate cancer associated with various vasectomy parameters. Results: The prevalence of vasectomy was similar in cases and controls (36.2% and 36.1%, respectively, adjusted OR 1.0, 95% CI 0.8–1.2). There were also no associations between prostate cancer and age at vasectomy, years elapsed since vasectomy or calendar year of vasectomy. Conclusions: These findings indicate that there is no association between vasectomy and the risk of prostate cancer. 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Volume 180Issue 6December 2008Page: 2565-2568 Advertisement Copyright & Permissions© 2008 by American Urological AssociationKeywordsprostatic neoplasmsprostatevasectomyriskMetricsAuthor Information Sarah K. Holt Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington More articles by this author Claudia A. Salinas Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington Department of Epidemiology, University of Washington, Seattle, Washington More articles by this author Janet L. Stanford Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington Department of Epidemiology, University of Washington, Seattle, Washington More articles by this author Expand All Advertisement PDF DownloadLoading ...